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Nutrition and the Skeleton: The Role of Calcium and Other Nutrients Nutrition is one of many factors that influence bone mass. Dietary intake can also impact the tendency to fall and plays a significant role in maintaining a soft tissue cushion to protect the skeleton from the impact of a fall. Calcium and Calcium Balance Bone serves as the reservoir for 99% of the body's total calcium. Calcium is an essential nutrient for bone health. It is also needed for the heart, muscles and nerves to function properly and for blood to clot normally. The body loses calcium every day through urine, feces, sweat and shed skin, hair and nails. The lost calcium is normally replaced by calcium in the diet. When the diet does not contain enough calcium to offset such losses, the body breaks down bone to release calcium needed to accommodate these physiologic demands. Many other nutrients affect bone health, too, because they impact the absorption or excretion of calcium. Calcium balance-not just intake-is necessary for healthy bones. This balance is dependent on the absorption rate of calcium consumed as well as the rate of (mostly urinary) calcium excretion. For example, in a study of 560 healthy women, one researcher demonstrated that only about 10 percent of the variance in calcium balance among these women was explained by differences in their calcium intakes and absorption only explained another 15 percent. Urinary losses explained slightly more then 50 percent. Nutrients Affecting Calcium Balance Several nutrients significantly influence calcium balance:
The Effects of Nutrition on Bone Density and Fracture Risk
Calcium and Vitamin
D Among postmenopausal women, studies have shown that supplemental calcium can decrease the rate of bone loss from the femoral neck, the spine and the total body. Women who have been postmenopausal for six or more years tend to reap a greater benefit from calcium supplementation than those who are within five years of menopause. Since calcium is a nutrient, not a drug, the positive effects of supplemental calcium are most pronounced among women with low to moderate calcium intakes. Recent clinical trials have suggested that supplementation with calcium or calcium plus vitamin D, can reduce fracture incidence by about 30-50% in subjects with low calcium intakes. Vitamin D deficiency is also a concern in bone health. The nutrient is essential for calcium absorption and normal bone mineralization. Studies have shown that low levels of vitamin D can contribute to low bone density. Recent evidence suggests that deficiencies in this nutrient may additionally contribute to hip fractures in postmenopausal women.
Protein and Bone
Health Reduced protein intake has been linked to low femoral neck bone density in elderly hospitalized patients. In these individuals, clinical outcomes following hip fracture were significantly enhanced when protein intake was normalized through nutritional supplementation.
Soy and
Isoflavones Chick peas and legumes are good sources of isoflavones. The legume, soy, has the greatest concentration of these chemicals. Isoflavones have received a good deal of attention for their possible cancer and heart disease-preventive traits. Because of their estrogen-like properties, many believe that isoflavones and other phytoestrogens may one day play a role in postmenopausal health. One isoflavone derivative, ipriflavone, is currently used outside of the United States as an osteoporosis therapy. Ipriflavone has had a bone-protective effect in several studies. Further research is needed to understand the systemic effects of this compound before it can be considered a therapeutic approach for osteoporosis prevention and treatment.
Nutrition and
Weight Body weight, is an important determinant of bone density. The skeleton of heavy individuals tends to benefit from it's increased load-carrying role. Studies have demonstrated that body weight is positively correlated with bone mineral density, and that weight loss is associated with bone loss. (Increasing calcium intake appears to reduce the bone loss that accompanies weight loss.) Weight loss in older individuals has been linked to an increase in fracture risk. Researchers found that "extreme" weight loss (10% or more) beginning at age fifty, increased the risk of hip fracture in older women and men. Conversely, a weight gain of 10% or more decreased hip fracture risk. Such studies suggest that maintaining weight in later life may have a protective effect on bone. |
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